Is the bioavailability of curcumin dependent on a healthy intestinal microbioma?
💡 The active ingredient Curcumin from the Turmeric is one of the most frequently examined plant substances, with not only his antioxidative and anti -inflammatory properties were confirmed, but also his antitumoral, liver protectors, neuroprotectives and lipid -modifying effects.
However, studies also found that his Bioavailability and bad solubility can reduce its effect.
💛 The better the Interactions between Intestinal and that Curcumin is the better it is Solubility and bioavailability And thus the therapeutic Effect!
Even with little absorption indicate a lot of data that Curcumin positive health effects on the Barrier capacity the Intestinal mucosa has and also high Concentrations of the bacterial LPS germs can reduce.
⛔ The poor availability of curcumin has been developing several in the past ten years Curcumin formulations led that could improve its bioavailability. These formulations include Curcumin nanoparticles, curcumin in lecithin, phosphatidylcholin carrier and solid lipid curcumin compounds.
In addition, studies pointed out that turmeric lecithin Products like healthy Vegetable oil or eggs should be combined to absorb Curcuminoids to increase through food.
Piperine is a Natural alkaloid, that in Black pepper (Piper Nigrum) occurs and is capable of the bioavailability of Curcumin to increase.
Unfortunately this combination with Piperine not tolerated in the case of histamine intolerance And should be avoided as an additive!
🤓 In some studies it has been shown that Nanoparticles such as nanocurcumin The best effects on the Intestinal microbiota Seems to have, as well as the best bioavailability for the body.
Source: https://www.ncbi.nlm.nih.gov/pmc/articles/pmc8230423/