Endometriosis and histamine intolerance
If you live with endometriosis, you already know how challenging and painful this disease can be. But maybe you haven't heard that histamine intolerance and the activity of your mast cells can play a crucial role in how you feel. In this article we take a closer look at how these aspects are related and what you can do to better control your symptoms.
What is endometriosis?
Endometriosis is one chronic disease, in the tissue that resembles the endometrium (the endometrium), grows outside the uterus. This fabric can be on different places in the abdomen Settling, including the ovaries, the fallopian tubes, the ligaments that support the uterus, the intestine, the bladder and in rare cases even outside the abdomen. Despite these different locations, the tissue behaves similarly to the endometrium in the uterus: it goes through the typical changes in the monthly cycle. This means that it thickens during the cycle and finally bleeding when you get your period. The difference, however, is that this tissue outside the uterus cannot simply be excreted out of the body. Instead, it stays where it is, and leads to inner bleeding. These bleeding are one of the main reasons why endometriosis is so painful. The blood and tissue that has no way out, can cause inflammation, irritate the affected areas and ultimately for the formation of Scar (Adhesions) and cysts. These cysts, also known as endometriomas, can Affect organswhere they settle and the Function of these organs disturb.
There are different theories, why endometriosis is created. One possibility is that Cells from the endometrium get to other areas of the body And get stuck there. Another theory says that a Imbalance of the hormones or the immune system can lead to endometriosis. Usually the immune system prevents cells from an organ from settling in the body elsewhere. There is also the assumption that Certain cells outside the uterus For reasons that are not yet fully understood can become endometrium cells. Since endometriosis occurs more often in some families, genetic factors could also play a role in the development of the disease.
Endometriosis can be in many different places in the body occur, the abdominal cavity is most often affected. The following areas are especially susceptible:
- Earthlocks: Endometriomas, often also referred to as "chocolate cysts", can be created here. These cysts are filled with old, dark brown blood and can become tall and painful.
- Toke ladder: Endometriosis in the fallopian tubes can affect their function, which leads to problems with fertility. The fallopian tubes can be blocked by the disease so that the egg cell can no longer get into the uterus.
- Colon: If endometriosis settles in the intestine, this can lead to digestive problems such as pain in bowel movements, diarrhea, constipation and in severe cases even to intestinal closures.
- Bladder and urinary tract: Endometriosis on the bladder or urinary tract pain when urinating, frequent urge to urinate or blood can cause the urine.
- Pelvic room: Endometriosis in the pelvic area can lead to chronic, persistent pain, which is often described as a duller, boring pain.
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Symptoms of endometriosis
- Pain in sexual intercourse
- Underbow and back pain before and during menstruation
- Float feeling during the period
- Disturbed cycle (intermediate bleeding, strong bleeding)
- Abdominal pain without connection with the period
- Fatigue and exhaustion
- Increased susceptibility to infections
- Blood in the urine and chair
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Why is endometriosis so difficult to diagnose?
Endometriosis is often as "Chameleon among gynecological diseases“Described because it can cause so many different symptoms that also occur in other diseases. Many of the Symptoms such as abdominal pain or digestive problemsare non -specific and can easily be confused with other diseases, such as irritable bowel syndrome or bladder infections. This can take years before the correct diagnosis is made. Another problem with the diagnosis is that the severity of the symptoms does not always match the extent of endometriosis. That means that some women with only few endometriosherds extremely severe pain can have while others With widespread endometriosis hardly any symptoms feel. This discrepancy makes it even more difficult for doctors to recognize and diagnose the disease. The Diagnosis of endometriosis is usually carried out by a combination of anamnesis, gynecological examination and imaging methods such as ultrasound or MRI. However, the safest way to diagnose endometriosis is one Abdominal mirroring (laparoscopy), in which the inside of the abdomen is examined with a camera. Tissue samples can also be removed to confirm the diagnosis.
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The role of mast cells in endometriosis
Now you may be wondering what mast cells have to do with endometriosis. Mast cells are special immune cells, which is an important role in the Defense of infections play. However, they are also known for releasing histamine - a substance that plays a major role in allergies and inflammation. So mast cells are usually quite useful. But if you are overactive, you can do the opposite and increase inflammation and pain.
In women with Endometriosis Did you find that many mast cells accumulate in the endometriosis herds. These overactive mast cells not only set histamine, but also others Inflammatory substances free that the surrounding Irritate the tissue and make the pain worse. Studies have shown that Mast cells are not just there, but Actively contribute to the development and progression of endometriosis. This means that the inflammation and pain you feel could be caused by the activities of these small but powerful cells.
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Histamine intolerance and endometriosis
There is indications that histamine intolerance could increase the symptoms of endometriosis. Women with endometriosis often report symptoms that are also typical of histamine intolerance, such as migraines, digestive disorders or allergy -like symptoms. A high histamine level can increase the inflammation in the body, which in turn could worsen the pain and symptoms of endometriosis. So a vicious circle arises: endometriosis causes more inflammation, these inflammation activate the mast cells, which in turn release even more histamine, which makes the symptoms worse. If mast cells play such a big role, there could be a way to regulate their activity. Come here Mast cell stabilizers into play. These medication Help prevent the release of histamine and other inflammatory substances from the mast cells. There are also natural substances that have a similar effect, such as quercetin, a plant substance that is contained in many fruits and vegetables. But before you use medication now, it is important to to discuss with a doctorwho are familiar with endometriosis and histamine intolerance. You can help you find out whether such treatment makes sense for you and what alternatives there are.
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The role of nutrition
Your diet can have a significant impact on how you feel. Certain foods are rich in histamine or Promote the release of histamine From the mast cells. This includes, for example, mature cheeses, fermented foods such as sauerkraut or soy sauce, alcohol, especially red wine, as well as processed meat products such as salami. If you think that histamine intolerance plays a role in you, it could make sense Avoid these foods And to observe whether your symptoms improve.
At the same time there is Foods that have an anti -inflammatory effect and the Can calm mast cells. Green leafy vegetables, berries, fish that is rich in omega-3 fatty acids, and spices such as turmeric could help to alleviate your symptoms. An anti -inflammatory and low -gluten diet that little meat and Dairy, but a lot Vegetables And freshness, unprocessed foods Contains, is often recommended for endometriosis And is also an advantage with histamine intolerance.
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Stress and its effects on mast cells
Endometriosis is not just one physical stress, but can also mentally Stroll heavily. The constant pain, the uncertainty about the diagnosis and the possible effects on fertility can be too Fears, depression and one reduced self -esteem lead. It is important to Support To search, be it Through conversations with other affected, one Self -help group or one psychological advice. When you are stressed, your body pours out cortisol, a hormone that, among other things, promotes the release of histamine. Chronic stress can therefore make your symptoms worse and continue to drive the vicious circle described above. It is therefore important Techniques to find, that help you reduce stress. Yoga, meditation, breathing exercises or just regular breaks in everyday life can work wonders. Also Movement It is helpful because it helps your body to reduce stress hormones and at the same time promotes blood circulation, which can have a positive effect on your symptoms.
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How you can better manage your symptoms
If you suffer from endometriosis, there are some practical steps that you can take to better control your symptoms:
1. Lead the diary: Write down when which symptoms appear and which food you have eaten. So you can better recognize possible relationships between your diet and your symptoms.
2. Experiment with a histamine and anti -inflammatory diet to see if your symptoms improve. Attempts to prefer freshness and unprocessed foods.
3. Mast cell stabilizers: Talk to your doctor about the opportunity to try mast cell stabilizers, especially if you have strong symptoms that could be connected to the release of histamine.
4. Stress management: Find ways to reduce your stress. Regardless of whether it is yoga, meditation, walks in nature or just reading a good book - whatever helps you come to rest is good for you.
5. Regular movement: Sport can help reduce stress and improve your blood circulation. He also supports your immune system and can help reduce inflammation. Avoid overexertion!
👉🏼 Endometriosis is one complex diseasethat affects many different aspects of your life. By understanding the role of histamine and mast cells, you can actively help to control your symptoms better. It may require a little experimentation and patience, but with the right nutrition, stress management and possibly also medical support you can significantly improve your everyday life. Many women report on a long suffering until they finally get the diagnosis of endometriosis. On average it takes seven to ten years before the disease is diagnosed. During this time, the women concerned often have had numerous visits to the doctor without receiving a clear explanation for their symptoms. They are often told that their pain is "normal" or that they should "not like this". This Misdiagnoses And the incomprehension Can not only make the physical, but also emotional stresses considerably worse. However, an early detection and treating endometriosis is crucial to avoid long -term complications and improve the quality of life. If you have the feeling that you could suffer endometriosis, it is important to stay stubborn and not let yourself be taken away. Check out a doctor who is familiar with the disease and responds to your symptoms.
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SOURCES
From those affected for those affected
We are Thomas and Michaela Zinser, founder of Histaminikus.
Because of the own histamine intolerance of Michaela and our son, we founded Histaminikus. The frustration does not find any suitable histamine food has spurred us to develop low -histamine food.
We would like to give you back a piece of quality of life. Feel free to look around with us.
Kind regards
Thomas and Michaela