
Joint pain and histamine
Joint pain is among the most common symptoms that can occur in everyday life - be it through mechanical stress, age -related changes or inflammatory processes, such as those in rheumatic diseases. Histamine can also play a role here. Around 400 different diseases now summarize doctors under the generic term "diseases of the rheumatic form" - including gout, lupus erythematosus, diseases of the vasculitis) and many more. Rheumatic diseases meet people of all ages, even children can already suffer from rheumatism.
What are joint pain?
Joint pain can be Warning signal of the body are understood and often in connection with inflammatory or degenerative Processes on. This is not a sudden illness, but changes that often develop over the years. You can find the joints as hinges or Connecting points Introduce that are burdened by external and inner influences. If the function of this “hinges” is impaired, pain, swelling and limited mobility can result. Joint pain is less to be understood as an independent disease, but rather than symptomthat can indicate various causes. So you can go through overload, inadequate regeneration, injuries or also by chronic diseases such as arthritis be triggered. Over time, these creeping changes can lead to the joint less resilient and the everyday mobility is affected.
Free joint pain is often rheumatic diseases or osteoarthritis. If from "rheumatism“Rheumatoid arthritis is usually meant. With this disease, several joints are generally inflamed. With advanced rheumatism, everyday things such as personal hygiene, eating with knives and fork or closing butt inflammatory processes In the body, histamine also plays a role in joint inflammation.
Osteoarthritis arises from the age -related Reduction of articular cartilage And not through inflammatory processes. A typical symptom is the so -called Start -up painwho appears after long periods of rest, for example after sitting or lying. This pain can occur again and again, but usually sounds again after a short time. In addition, the symptoms are particularly noticeable when moving, while the joints usually remain painless in peace.
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Causes of joint pain
The causes of joint pain are diverse and can be roughly divided into three categories:
👉🏼 Inflammatory processes
The exact causes of rheumatoid arthritis have not yet been fully researched. However, it is certain that misguided autoimmune processes are involved. The immune system incorrectly attacks the body's own tissue, whereby certain messenger substances, so -called interleukins, stimulate immune cells to immigrate into the joints. There they trigger inflammatory reactions that cause the inner skin to grow and scarred increasingly. In the course, cartilage and ligaments are damaged, which causes pain and movement restrictions.
👉🏼 Mechanical overload
Repeated loads, accidents or injuries can lead to acute or chronic damage to the joints. Overuse of individual joints, for example through sports or physical work, can lead to complaints in the long term.
👉🏼 Degenerative changes
With increasing age, the joints, which is referred to as osteoarthritis, lead to natural wear. This wear and tear leads to a decrease in the joint function and can contribute to pain in combination with other factors.
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Trigger in connection with histamine
More and more Research results indicate that histamine not only in classic allergies, but also in Context of joint pain and rheumatic batches plays a role. Recent studies suggest that a increased histamine level Can increase inflammatory processes in the joints. A research team from the Bonn-Rhein-Sieg University of Applied Sciences examined this in more detail. In the inflamed joints of those affected, many mast cells were discovered that release histamine. This could increase the inflammation and possibly trigger disease spurts. In one experiment it was found that the blockade of a certain Histamine receptor, the H4 receptorcould prevent the development of the disease.
The study suggests that histamine is not only a side effect of the disease, but could be directly involved in the inflammatory processes. This opens up new opportunities for treatment-for example by medication that specifically inhibits the H4 receptor.
Through the histamine -related Expansion of the blood vessels the blood circulation in the affected joint is also increased. On the one hand, this can Pollutants favor, but also too Fluid accumulation And lead swelling that increase the pain.
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First signs and symptoms
The symptoms of joint pain do not refer exclusively to pain that can vary greatly in the intensity. There are other symptoms:
- Swelling and redness - a visible swelling or redness in the affected area can indicate an inflammatory reaction.
- Restricted mobility - if you notice that the mobility of the joints subsides, this could be an indication of increased inflammatory activity.
- Heat feeling - affected joints can feel warmer than the surrounding tissue.
Similar to other inflammatory processes, these symptoms can begin gradually and intensify over time if no suitable measures are taken.
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Diagnosis and clarification
If you repeatedly suffer from joint pain, it is important that To have causes to be clarified by a doctor. One Precise diagnostics usually includes a Anamnesis, in which your doctor asks your doctor in detail when exactly the pain occurs, what possible triggers there is and whether there is Family preload present. Also earlier injuries as well chronic diseases can provide valuable information. In addition to the anamnesis, one clinical examination carried out. Here the doctor checks the mobility of the affected joints and searches for other signs that are on one inflammation or damage indicate. In addition, imaging procedures such as X -rays, Ultrasound examinations or mrts Use to make structural changes visible in the joints.
In the case of rheumatic diseases in particular, these examinations are important in order to Severity and the course of the inflammation to assess. Also can Laboratory tests be necessary, especially Blood teststhat provide information about whether inflammatory processes take place in the body. Become Inflammatory marker as well as specific antibodies measured that can indicate rheumatic diseases.
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Treatment options of rheumatism
The treatment of joint pain requires one holistic and individually coordinated approachthat often both medication as well as non-medicament Measures include. First of all, the focus is on determining the exact cause, since the therapy depending on the underlying disease - be it a Inflammatory rheumatic disease, one degenerative change like arthrosis or a Overload of the joints - can be different. Come in many cases anti -inflammatory medication to use how non -steroidal anti -rheumatics (Nsar) or Corticosteroidthat specifically reduce the inflammatory processes in the affected joints and thus reduce pain and swelling. Due to the research on Connection between histamine and rheumatism it is conceivable that in the future maybe too Antihistamines could be used. Chronic rheumatic diseases are common Disease -modified anti -inflammatory drugs used to influence the course of the disease in the long term. In the advanced stage there is a person with some rheumatism Operation essential, in the destroyed joints by a prosthesis replaced or, if this is not possible, for example.
In addition to drug therapy Physiotherapy be meaningful. Through targeted exercises and manual therapy, the agility The joints improved, strengthened the muscles and increases stability, which not only reduces pain, but also counteracts further deterioration. In addition, Alternative procedure How acupuncture, Heat therapy or cold therapy contribute to pain relief because you can promote blood circulation and have a positive impact on the sensation of pain.
Also one Adaptation of the lifestyle should take place. One balanced diet, which contains anti -inflammatory foods, can affect the joint state cheaply. It should be taken into account Avoiding foods that promote inflammation Or favor an increased histamine level. Individual nutritional strategies, such as leading a Nutrition diaryhelp to identify personal triggers. In addition, the body weight contributes significantly to the stress of the joints; It is therefore advisable to strive for a healthy weight so as not to unnecessarily strain the joints.
The one should also not be underestimated Influence of stress on joint pain. Stress can not only increase the sensation of pain, but also by the Release of stress hormones and histamine worsen the associated inflammatory processes and symptoms. Relaxation techniques such as yoga, meditation or progressive muscle relaxation offer effective ways to lower the stress level and thus also relieve the symptoms.
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SOURCES
- https://www.gesundheitsinformation.de/rheumatoide-arthritis.html
- https://www.ndr.de/ratgeber/gesundheit/Rheuma-Symptome-und-Behandlung-bei-rheumatoider-Arthritis,rheuma172.html
- https://www.h-brs.de/de/pressemitteilung/histamin-scheint-rheumatische-schube-auszulosen
- https://www.liebscher-bracht.com/schmerzlexikon/tipps/histamin/
- https://de.wikipedia.org/wiki/Rheuma

From those affected for those affected
We are Thomas and Michaela Zinser, founder of Histaminikus.
Because of the own histamine intolerance of Michaela and our son, we founded Histaminikus. The frustration does not find any suitable histamine food has spurred us to develop low -histamine food.
We would like to give you back a piece of quality of life. Feel free to look around with us.
Kind regards
Thomas and Michaela