
DAO mining disruption - cause of histamine intolerance
Treat a DAO reduction disorder naturally
One DAO subscription weakness is the most common cause of histamine intolerance. The DAO (Diaminoxydase) is one of two histamine -reducing enzymes, which is mainly formed in the small intestine and in the placenta. It is responsible for reducing histamine and other biogenic amine in the intestine.
In the case of a reduced activity of the DAO, too much histamine enriches not only in the intestine but also in the blood and leads to a wide variety of symptoms.
What is a histamine intolerance
Histamine intolerance arises if there is too much histamine in the body and cannot be sufficiently broken down. Histamine is either absorbed through histamine -rich food or formed even in the body. An excess of histamine can lead to diverse symptoms such as asthma, skin diseases, gastrointestinal complaints, irritable bowel, but also fear and panic attacks.
It is particularly important to find the cause of histamine intolerance, since the histamine intolerance is only a symptom.
One of these causes can be a DAO subscription weakness. Studies (1) have shown that in 70% of the cases a DAO subscription weakness is responsible for histamine intolerance.
How can I diagnose a DAO subscription weakness?
To clarify a suspicion of the existence of a DAO subscription weakness, the following laboratory examinations can be carried out:
- Determination of histamine in the blood,
- Determination of histamine in the chair as well
- Determination of the DAO activity in the blood.
A reference to a DAO subsidy weakness is given for the following laboratory measurement values:
- Histamine in the blood normal or increases in the case of reduced DAO activity in the blood,
- Increasing histamine in the blood,
- Histamine increased in the chair.
Symptoms of a DAO diligence
In the case of a DAO absorption, the following symptoms often occur. Not all symptoms have to occur at the same time and immediately after eating. The symptoms can also appear up to 72 hours after eating.
Studies have confirmed that 20% of patients report 1 or 2 symptoms, 41.3% of patients from 3 to 4 symptoms and 33.8% of more than 5 symptoms.
The most common symptoms of reduced DAO activity look as follows:
- Migraines or other headaches
- Gastrointestinal diseases, irritable bowel syndrome, constipation, diarrhea, over-saturation, flatulence, flatbread
- Skin problems such as dry skin, atopia or psoriasis
- Fibromyalgia
- Chronic exhaustion
- ADHD - especially in childhood and youth
- Bronchial asthma, gasps, respiratory diseases
Causes of a DAO diligence
- Genetic factors -In some, genetic mutations cause a DAO subscription weakness. Whether there is a genetic disorder can be examined using a laboratory test.
- Medication -Different drugs can act as DAO blockers and thus disturb the enzyme in its function. It is therefore important to find out carefully whether the medication prescribed by the doctor blocks the DAO. Dao inhibitors are, for example, acetylsalicylic acid (ASS), diclofenac, indometacine, hall bib process, ketoprofen, meclofenamic acid, mefenamic acid, naproxen.
- Hormonal imbalance - An imbalance in the interaction between estrogen and progesterone can lead to a histamine surplus. See also ours Contribution to hormones.
- Gastrointestinal diseases - Diseases such as irritable bowel syndrome, Crohn's disease, colitis, celiac disease and Sibo can cause inflammation in the intestinal mucosa. An inflamed intestinal mucosa cannot form a DAO and therefore not sufficiently reduce histamine.
- Vitamin deficiency - The DAO needs vitamin C, vitamin B6, copper and zinc to function properly. A lack of this fabrics leads to a DAO subscription weakness.
- Histamine -rich nutrition / biogenic amine -Some foods inhibit the DAO enzyme or ensure a surplus of histamine, so that the enzyme is no longer able to reduce this surplus. The DAO is also for the reduction of biogenic amines (e.g. serotonin, tyramine, putrescin, and much more) responsible. It even prefers to dismantle biogenic amine, whereas the breakdown of histamine only takes place slowed down. A diet that contains many biogenic amine and histamine can overwhelm the DAO in the long run.
- alcohol -Alcohol is one of the most famous DAO blockers at all and should therefore be avoided.

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How can I naturally boost the DAO?
Low -histamine diet
A long-term study (2) follows one Strict -having low -histamine nutrition for the fact that in most cases the Dao normalized again within a year. By dispensing with histamine -rich food, you allow the body to break down the existing histamine and thus to empty the histamine barrel bit by bit. It is also important to avoid inhibiting food. These are in particular alcohol, black tea, green tea, mate tea, cocoa, energy drinks and nutmeg. When choosing food, make sure that they are fresh, natural and best in organic quality. Chemical additives and pesticides can also interfere with the DAO in terms of functioning and also affect health.
If you are not sure Which foods you should eat with a histamine intolerance and which not, then we will be happy to refer you to ours Grocery list. There you will receive the necessary information.
Compensate for fat consumption
Research (3) has found that there is an interesting connection between fat consumption and the DAO activity. Especially the Oleic acid Has one positive effect on the DAO activity And increases the release of the enzyme into the bloodstream by a fabulous 500%. The oleic acid is one of theOmega-9 fatty acidsand is mainly in olive oil to find. But also Rapeseed oil Contains an amazingly large amount of oleic acid. It is best to get used to olive oil every day To take you, either pure or in the salad. You do something really good for your Dao-Ezym.
Anti -inflammatory diet
Histamine triggers inflammation and one Inflammated intestinal mucosa does not form DAO. So eat low -inflammatory Food and rely on anti -inflammatory herbs such as turmeric, chamomile and sage if they are compatible. Avoid also for a while Dairy products, eggs and red meat, because these foods are inflammatory.
Pay attention to intestinal health
As already mentioned, the DAO in the small intestine is produced in the intestinal mucosa. A healthy intestinal mucosa and the support of the intestine with Histamin -reducing bacteria form a good one The basis for alleviating histamine symptoms. In the case of an inflamed intestinal mucosa, the enzyme DAO is often missing in order to reduce histamine and other biogenic amines. An imbalance between the intestinal bacteria can also cause unwanted bacteria to produce histamine or other biogenic amines and thus begin inflammatory processes. An intestinal flora status shows which intestinal bacteria are missing or are too much available. A good probiotics helps that Darmflora back into balance bring to.
Dietary supplements
Zinc, copper, vitamin B6 and vitamin C belong to the so -called DAO coofactors, This means that the enzyme cannot work properly without these nutrients. It is recommended to have the status of these nutrients determined by the doctor or alternative practitioner. If there is a deficiency, the regular use of these nutrients can stimulate DAO again and relieve histamine symptoms.
Our HISTAPREVENT® Contains the DAO coofactors and helps to build up a lack of vitamin C, B6 and zinc.
DAO dietary supplement
In the meantime there are already various DAO dietary supplements such as Daosin, Dao-Ezym, etc. It can make sense to take this dietary supplement for a while to increase the activity of the DAO. Now you have 6 tips on hand on how you can of course boost your DAO. I would like to encourage you to apply these simple methods every day and start immediately. They are very easy to carry out and lead to positive effects. So let's go.
Collapsible content
Sources
(1) https://www.ncbi.nlm.nih.gov/pubmed/26574488
(2) https://www.ncbi.nlm.nih.gov/pubmed/23579881
(3) https://pdfs.semanticscholar.org/ef3b/3cc7a617bdd6672581c35896a35e22492a95.pdf
We have to point out that all information on treatment methods, nutrients and vitamins and their effects relate to traditional knowledge, studies and opinions and experiences of therapists and literature. Our contribution cannot replace medical healing treatment with the diagnosis and therapy of a doctor. We cannot give a healing promise either. It is primarily about passing on information. In the event of serious illnesses, non -explanatory symptoms and uncertainty, you should see a doctor. The nutrients or forms of therapy mentioned are used for your own dangers. Everyone has to decide for themselves what and whether they have it!

From those affected for those affected
We are Thomas and Michaela Zinser, founder of Histaminikus.
Because of the own histamine intolerance of Michaela and our son, we founded Histaminikus. The frustration does not find any suitable histamine food has spurred us to develop low -histamine food.
We would like to give you back a piece of quality of life. Feel free to look around with us.
Kind regards
Thomas and Michaela