When you live with endometriosis, you already know how challenging and painful this disease is. But maybe you haven't heard that histamine intolerance and the activity of your mast cells can play a crucial role in how you feel ...
Affected people of a hit or MCAS have a wide variety of individual stimuli that trigger and reinforce their symptoms. These triggers usually go far beyond unsuitable food. As trigger, penetrating fragrance, odor and other pollutants are also possible, favoring the stress and activation of mast cells in the body.
With mastocytosis there is a pathological accumulation and activation of mast cells in the bone marrow, in the skin, in the musculoskeletal system or in the internal organs such as spleen, liver, lymph nodes and gastrointestinal tract.
Colon symptoms such as constipation and diarrhea are among the main symptoms of histamine intolerance. And this is also understandable, since there are large amounts of mast cells in the intestine and the histamine -degrading enzyme dao is formed in the intestinal mucosa.
Studies have proven that estrogen triggers the activation of mast cells. But estrogen not only ensures that histamine is released from the mast cells, it also weakens the DAO.
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